BDP 331Basic Dispensing Practicals III

Pastes: The Practical

8 minute read

What you will learn

  • Define a paste and say how it differs from an ointment
  • List the uses of pastes
  • Make a paste by mixing powders into a base
  • Scale a paste formula
  • Pack, label and store a paste
  • Recognise faults in a paste

Key points

  • A paste is a stiff semi-solid with a large amount of fine powder, usually 25% or more, in an ointment base.
  • Pastes are stiffer and less greasy than ointments, and stay in place.
  • They absorb fluid, protect the skin, and are used on small areas, such as for napkin rash or eczema.
  • Powders must be fine and well mixed with the base.
  • A paste is made by adding the powders to the softened base on a tile, little by little.
  • Pastes are packed in wide-mouthed jars, and applied with a spatula.
  • They are for external use only, and are not used on hairy areas.

What is a paste?

A paste is a stiff semi-solid that contains a large proportion of finely powdered solids, usually 25% or more, spread in a greasy base (or sometimes a water-based one). It is firmer than an ointment.

OintmentPaste
Powder contentNone, or smallLarge (about 25% or more)
TextureSoft and greasyStiff and less greasy
SpreadingSpreads easilyStays where it is put
Absorbs fluidLittleAbsorbs secretions
UseSoften, protect, carry drugsProtect, absorb, treat small patches

Uses

  • To protect the skin, for example in napkin rash.
  • To absorb moisture and discharges.
  • To treat small, well-defined areas of skin disease such as eczema or psoriasis, because the paste stays on the patch and does not spread.
  • To act as a barrier against irritants.

A paste is not used on hairy areas, because it is hard to remove, and not on large areas or weeping wounds unless directed.

Example: zinc and salicylic acid paste

Typical formula: salicylic acid 2%, zinc oxide 24%, starch 24%, white soft paraffin 50%. Use the formula your school gives you.

Scaling

Make 50 g.

  1. Salicylic acid = 50 × 2 ÷ 100 = 1 g
  2. Zinc oxide = 50 × 24 ÷ 100 = 12 g
  3. Starch = 50 × 24 ÷ 100 = 12 g
  4. White soft paraffin = 50 × 50 ÷ 100 = 25 g

Check. 1 + 12 + 12 + 25 = 50 g. The percentages add to 100%: 2 + 24 + 24 + 50 = 100.

Method

  1. Weigh all the ingredients.
  2. Sieve or powder the solids very finely, so there is no grit.
  3. Mix the powders together on a tile with a spatula, starting with the smallest quantity (the salicylic acid) and adding the larger ones (geometric dilution).
  4. Soften the base by working it with the spatula, or by warming it very gently if it is too stiff. Do not melt it unless the formula says.
  5. Add the powder to the base in portions, working each portion in thoroughly until the paste is smooth and even.
  6. Pack into a wide-mouthed jar, pressing out air gaps.
  7. Label the jar.

Why add the powder to the base?

Adding the powder to the base in stages wets each particle properly and gives a smooth, uniform paste. Adding all the base to all the powder at once makes lumps and gritty patches.

Packing, labelling and storage

  • Pack in a wide-mouthed jar with a tight lid, because the paste is stiff and hard to remove from a tube.
  • Label: patient's name, name and strength of the paste, directions, "For external use only", the date, and a discard date.
  • Store in a cool place.
  • Tell the patient: wash hands before and after use, apply with a clean spatula or gloved finger, and use a thin layer. Do not put it near the eyes or on broken skin unless told to do so.
  • Salicylic acid can irritate healthy skin around the patch, so apply it only to the affected area.

Faults and what to do

FaultLikely causeWhat to do
Gritty pasteThe powders were too coarse, or not sievedPowder and sieve them again
LumpsPowder added all at onceAdd in portions, mixing well
Paste too stiffToo much powder, or a cold baseCheck the weights, and warm the base very gently
Paste too softToo little powder or too much baseCheck the weights
Uneven colourPoor mixingContinue mixing until smooth

Exam focus

  • State how a paste differs from an ointment.
  • Describe the method for making a paste.
  • Scale a paste formula, such as zinc and salicylic acid paste.
  • Common mistake: using powders that are too coarse, which makes a gritty paste that irritates the skin.

Quick check

Test yourself before you move on. Pick an answer to see the explanation.

  1. 1.A paste differs from an ointment because it:

  2. 2.Zinc and salicylic acid paste has zinc oxide 24%, starch 24%, salicylic acid 2% and white soft paraffin 50%. How much white soft paraffin is in 50 g?

  3. 3.In the same paste, how much zinc oxide is in 50 g?

  4. 4.Why should powders for a paste be made very fine?

  5. 5.A paste is best applied with:

Practise past questions